Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
riok2RIO domain-containing protein. (516 aa)    
Predicted Functional Partners:
bysl
Bystin-like.
   
 0.999
ltv1
LTV1 ribosome biogenesis factor.
   
 0.999
nob1
NIN1 (RPN12) binding protein 1 homolog.
   
 0.999
riok1
Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
   
0.993
riok3
Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
   
0.987
tsr1
TSR1 ribosome maturation factor.
   
 0.986
rrp12
Ribosomal RNA processing 12 homolog.
   
 
 0.979
rps3
Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
    
 0.976
rps2
Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.
    
 0.970
rps15
Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.
    
 0.954
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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