Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
rab27aRAB27A, member RAS oncogene family. (220 aa)    
Predicted Functional Partners:
H2LLD4_ORYLA
Synaptotagmin-like 2a.
   
 0.792
LOC101169380
Uncharacterized protein.
   
 0.792
sytl1
Synaptotagmin-like 1.
   
 0.792
LOC101158129
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
    
 0.790
cd63
Tetraspanin.
     
 0.761
LOC101164255
Si:ch211-106h4.9.
    
 0.751
myo5a
Myosin VAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 0.738
madd
MAP-kinase activating death domain.
     
 0.721
rabggta
Rab geranylgeranyltransferase subunit alpha.
    
 0.719
sytl5
Synaptotagmin-like 5.
    
 0.716
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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