STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rab27aRAB27A, member RAS oncogene family. (220 aa)    
Predicted Functional Partners:
LOC101158129
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
    
 0.707
rabggta
Rab geranylgeranyltransferase subunit alpha.
     
 0.681
madd
MAP-kinase activating death domain.
     
 0.667
cd63
Tetraspanin.
     
 0.667
LOC101164255
Si:ch211-106h4.9.
    
 0.611
myo5a
Myosin VAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 0.575
ap3b1
AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.
      
 0.560
hps5
Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
      
 0.560
hps4
HPS4 biogenesis of lysosomal organelles complex 3 subunit 2.
      
 0.560
hps3
HPS3 biogenesis of lysosomal organelles complex 2 subunit 1.
      
 0.560
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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