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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101173781Tetraspanin. (236 aa)    
Predicted Functional Partners:
LOC101162281
Immunoglobulin superfamily, member 8.
    
 
 0.779
ENSORLP00000028318
Ig-like domain-containing protein.
    
 
 0.716
ptgfrn
Uncharacterized protein.
    
 
 0.716
LOC101156484
Tetraspanin.
  
 
 
0.699
LOC101175317
Tetraspanin.
  
 
 
0.694
itga3
Integrin, alpha 3b; Belongs to the integrin alpha chain family.
   
 0.652
cd63
Tetraspanin.
  
 
0.646
cd36
CD36 molecule (thrombospondin receptor); Belongs to the CD36 family.
   
 0.611
LOC100125525
Uncharacterized protein.
    
 0.597
slc37a4
Solute carrier family 37 member 4a.
   
  
 0.582
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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