Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dennd1bDENN/MADD domain containing 1B. (868 aa)    
Predicted Functional Partners:
rab35
RAB35, member RAS oncogene family b.
    
 0.869
LOC101155198
Si:dkey-16l2.16.
    
 0.815
dennd2c
DENN/MADD domain containing 2C.
   
 
 0.637
rab28
Uncharacterized protein.
     
 0.612
dennd1a
DENN/MADD domain containing 1A.
     
 0.602
rab21
RAB21, member RAS oncogene family.
      
 0.585
LOC101165659
14_3_3 domain-containing protein; Belongs to the 14-3-3 family.
     
  0.579
LOC101175099
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family.
     
  0.579
LOC101158129
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
   
 
  0.579
ift27
Intraflagellar transport 27.
    
 0.553
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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