STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gnao1Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b. (354 aa)    
Predicted Functional Partners:
ednr
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
    
 0.914
LOC101158386
Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family.
    
 0.914
LOC100049225
Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family.
    
 0.914
dvl3
Dishevelled segment polarity protein 3a.
    
 0.903
dvl2
Dishevelled segment polarity protein 2.
    
 0.903
dvl1
Dishevelled segment polarity protein 1a.
    
 0.903
gnb3
Guanine nucleotide binding protein (G protein), beta polypeptide 3a.
   
 0.873
H2LGY1_ORYLA
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 0.850
LOC101168199
WD_REPEATS_REGION domain-containing protein.
   
 0.845
LOC101175500
Guanine nucleotide binding protein (G protein), beta polypeptide 2.
   
 0.845
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.