Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101160555Toll-like receptor 9; Belongs to the Toll-like receptor family. (1098 aa)    
Predicted Functional Partners:
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
    
 0.991
TLR8
Toll like receptor 8.
     
0.912
LOC101169500
Toll-like receptor 7; Belongs to the Toll-like receptor family.
  
  
 
0.903
LOC101158892
Interferon regulatory factor 3.
     
 0.722
il10
Interleukin 10.
   
 
 0.696
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.681
irak4
Interleukin-1 receptor-associated kinase 4.
    
 0.655
tirap
Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.
   
 0.652
nod2
Nucleotide-binding oligomerization domain containing 2.
    
 
 0.643
pik3ap1
Phosphoinositide-3-kinase adaptor protein 1.
   
 
 0.596
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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