Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pdp1Pyruvate dehyrogenase phosphatase catalytic subunit 1. (525 aa)    
Predicted Functional Partners:
pdpr
Pyruvate dehydrogenase phosphatase regulatory subunit.
  
 0.849
LOC101165911
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.797
LOC101174054
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.797
pdhx
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.793
pdhb
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.780
sardh
Sarcosine dehydrogenase.
  
 0.743
dlat
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.726
dld
Dihydrolipoyl dehydrogenase.
   
 0.721
LOC101166409
Si:ch211-114c12.2.
    
 0.716
dmgdh
Dimethylglycine dehydrogenase.
  
 0.650
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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