Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
thap11THAP domain containing 11. (274 aa)    
Predicted Functional Partners:
znf143
Zinc finger protein 143b.
     
 0.945
mcm3
DNA helicase; Belongs to the MCM family.
   
 
 0.814
gins1
GINS complex subunit 1 (Psf1 homolog).
    
 
 0.809
gins4
DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.
   
 
 0.796
gins2
DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.
   
 
 0.794
mcm2
DNA helicase; Belongs to the MCM family.
   
 
 0.791
mcm9
Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family.
   
 
 0.791
cdc45
CDC45 cell division cycle 45 homolog (S. cerevisiae).
   
 
 0.783
mcm5
DNA helicase; Belongs to the MCM family.
   
 
 0.773
mcm4
DNA helicase; Belongs to the MCM family.
   
 
 0.770
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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