STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101172288Amyloid beta (A4) precursor protein b. (738 aa)    
Predicted Functional Partners:
sorl1
Sortilin-related receptor, L(DLR class) A repeats containing.
    
 0.979
LOC101161673
Apolipoprotein Eb.
    
 0.971
snca
Uncharacterized protein; Belongs to the synuclein family.
    
 0.955
aplp2
Amyloid beta (A4) precursor-like protein 2.
   
  0.944
LOC101167562
Beta-secretase 2; Belongs to the peptidase A1 family.
    
 0.909
NCSTN
Nicastrin.
    
 0.903
LOC101170271
Nerve growth factor receptor a (TNFR superfamily, member 16).
    
 
 0.902
bace1
Beta-secretase 1; Belongs to the peptidase A1 family.
    
 0.884
psenen
Presenilin enhancer, gamma-secretase subunit.
    
 0.881
ppid
Peptidylprolyl isomerase D.
    
 
 0.867
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.