Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC101168078Receptor-interacting serine-threonine kinase 3; Belongs to the protein kinase superfamily. (481 aa)    
Predicted Functional Partners:
casp8
Uncharacterized protein; Belongs to the peptidase C14A family.
   
 0.996
ripk1
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
  
 
0.992
LOC100125536
Uncharacterized protein; Belongs to the peptidase C14A family.
   
 0.990
LOC101160750
Protein kinase domain-containing protein.
   
0.989
fadd
Uncharacterized protein.
   
 0.956
tnfaip3
Tumor necrosis factor, alpha-induced protein 3.
   
 0.951
LOC101154981
Toll-like receptor adaptor molecule 1.
   
 0.943
LOC101169506
Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2.
    
 0.935
hsp90ab1
Heat shock protein 90, alpha (cytosolic), class B member 1.
    
 0.935
tradd
Tnfrsf1a-associated via death domain.
    
 0.924
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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