STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sos2Son of sevenless homolog 2 (Drosophila). (1323 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
   
 0.997
hras
HRas proto-oncogene, GTPase a.
   
 0.966
LOC101154954
Zgc:55558.
   
 0.966
kras
GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation.
   
 0.966
LOC101169984
Receptor protein-tyrosine kinase.
    
 0.965
egfr
Receptor protein-tyrosine kinase.
    
 0.965
fgfr1
Fibroblast growth factor receptor.
    
 0.962
fgfr3
Fibroblast growth factor receptor.
    
 0.954
fgfr2
Fibroblast growth factor receptor.
    
 0.950
mras
Muscle RAS oncogene homolog.
   
 0.947
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.