STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mc1rMelanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (334 aa)    
Predicted Functional Partners:
pomc
Proopiomelanocortin.
    
 0.991
LOC101164777
Uncharacterized protein.
    
 0.991
GNAS
Uncharacterized protein.
    
 0.932
LOC101166373
GNAS complex locus.
    
 0.932
TYR
Tyrosinase.
    
 0.846
tyr
Tyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds.
    
 0.845
LOC101155370
Doublecortin-like kinase 1b.
    
 0.834
LOC101167140
Doublecortin-like kinase 1a.
    
 0.834
tyrp1
Tyrosinase related protein 1.
    
 0.810
oca2
CitMHS domain-containing protein.
      
 0.810
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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