STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aup1AUP1 lipid droplet regulating VLDL assembly factor. (417 aa)    
Predicted Functional Partners:
ube2g2
Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.953
derl2
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
   
 
 0.840
sel1l
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
   
 
 0.818
ankrd50
Ankyrin repeat domain 50-like.
    
 
 0.814
LOC101170859
DEAQ box RNA-dependent ATPase 1.
 
    
 0.812
poll
Polymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family.
      
 0.756
LOC101160343
Zgc:123010.
   
  
 0.724
syvn1
Synovial apoptosis inhibitor 1, synoviolin.
    
 0.709
faf2
Fas associated factor family member 2.
    
 
 0.700
loxl3
Lysyl oxidase-like 3b.
    
 
 0.662
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.