STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1242 aa)    
Predicted Functional Partners:
LOC101168718
Uncharacterized protein.
    
 0.961
LOC101161353
Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).
    
 0.961
LOC101167719
Uncharacterized protein.
    
 0.952
Itpr2
Inositol 1,4,5-trisphosphate receptor, type 2.
   
 0.918
LOC101167700
Inositol 1,4,5-trisphosphate receptor, type 1a.
   
 0.918
LOC101162627
G protein-coupled receptor, class C, group 6, member A.
     
 0.914
casr
Calcium-sensing receptor.
     
 0.914
LOC105357196
G_PROTEIN_RECEP_F3_4 domain-containing protein.
     
 0.914
INPP5A
Inositol polyphosphate-5-phosphatase A.
   
 
 0.910
LOC101159287
Calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2.
   
 0.908
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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