STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thumpd1THUMP domain containing 1. (306 aa)    
Predicted Functional Partners:
nat10
RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
   
 0.908
trub1
TruB pseudouridine (psi) synthase family member 1.
   
 
 0.714
alg9
Ferredoxin-fold anticodon binding domain containing 1.
   
 
 0.671
trmt1
tRNA (guanine(26)-N(2))-dimethyltransferase.
    
 
 0.654
trmt1l
tRNA (guanine(26)-N(2))-dimethyltransferase.
    
 
 0.654
dus2
Dihydrouridine synthase 2.
   
 
 0.652
pus1
Pseudouridine synthase 1.
   
 
 0.551
dkc1
Dyskeratosis congenita 1, dyskerin.
   
 
 0.519
trub2
TruB pseudouridine (psi) synthase family member 2.
   
 
 0.498
maf1
Zgc:112356.
    
 
 0.456
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.