STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101166763Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 1. (316 aa)    
Predicted Functional Partners:
gclc
Glutamate-cysteine ligase, catalytic subunit.
   
 0.677
gsta4
Uncharacterized protein; Belongs to the GST superfamily.
   
 
 0.577
psmc1
Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.
  
  
 0.565
nsmaf
Neutral sphingomyelinase (N-SMase) activation associated factor.
   
  
 0.534
NPTX1
Uncharacterized protein.
      
 0.520
psma1
Proteasome endopeptidase complex.
      
 0.509
LOC101165876
Ubiquitin protein ligase E3A.
      
 0.505
UBE3A
Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.
      
 0.505
pdcd4
Programmed cell death 4b.
      
 0.503
dhcr7
7-dehydrocholesterol reductase.
      
 0.480
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.