STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
raf1Raf-1 proto-oncogene, serine/threonine kinase a. (677 aa)    
Predicted Functional Partners:
map2k2
Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.
   
0.981
map2k1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
   
0.981
LOC101154954
Zgc:55558.
   
 0.977
kras
GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation.
   
 0.977
hras
HRas proto-oncogene, GTPase a.
   
 0.976
ksr1
Kinase suppressor of ras 1a.
    
0.972
mras
Muscle RAS oncogene homolog.
   
 0.965
rras2
RAS related 2.
   
 0.965
LOC101174431
RAS related.
   
 0.962
SRC
Tyrosine-protein kinase.
  
0.955
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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