STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sox17SRY-box containing gene 17. (398 aa)    
Predicted Functional Partners:
lef1
Lymphoid enhancer-binding factor 1.
    
0.963
tcf7
Transcription factor 7.
    
0.957
tcf7l1
HMG box domain-containing protein.
    
0.944
LOC111948314
HMG box domain-containing protein.
    
0.944
LOC100049520
POU domain protein.
    
 0.736
foxa2
Hepatocyte nuclear factor 3-beta; Transcription activator for a number of liver genes. Interacts with the cis-acting regulatory regions of these genes (By similarity).
    
 
 0.730
nanog
Homeobox domain-containing protein.
    
 0.692
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.690
gata6
GATA binding protein 6.
   
 0.667
gata4
GATA binding protein 4.
   
 0.624
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (16%) [HD]