STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101164501ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (159 aa)    
Predicted Functional Partners:
limk2
LIM domain kinase 2.
   
 0.980
LOC101162943
LIM domain kinase 1b.
   
 0.969
LOC101168921
Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.
   
 0.951
LOC101173727
Slingshot protein phosphatase 2a.
    
 0.913
LOC101161425
Slingshot protein phosphatase 1b.
    
 0.913
LOC101165662
Slingshot protein phosphatase 2b.
    
 0.913
ssh1
Slingshot protein phosphatase 1a.
    
 0.913
ssh3
Si:ch211-203d1.3.
    
 0.913
cfl1
Cofilin 1; Belongs to the actin-binding proteins ADF family.
  
  
 
0.905
LOC101159957
Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family.
  
  
 
0.905
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.