STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serpinf1SERPIN domain-containing protein; Belongs to the serpin family. (405 aa)    
Predicted Functional Partners:
lrp5
Low density lipoprotein receptor-related protein 5.
    
 0.908
lrp6
Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family.
    
 0.908
LOC101174098
Interferon induced transmembrane protein 5.
   
 0.733
LOC101170246
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.729
LOC101159701
Peptidylprolyl isomerase.
   
 
 0.701
LOC101170231
SERPIN domain-containing protein; Belongs to the serpin family.
  
  0.607
stil
SERPIN domain-containing protein; Belongs to the serpin family.
  
0.603
ENSORLP00000040252
SERPIN domain-containing protein; Belongs to the serpin family.
  
  0.603
proc
Protein C (inactivator of coagulation factors Va and VIIIa), a.
   
 0.592
ENSORLP00000045882
SERPIN domain-containing protein; Belongs to the serpin family.
  
  0.590
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.