htr2a protein (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

htr2a

5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a. (487 aa)

Predicted Functional Partners:

LOC101165845

0.980

htr2b

0.970

LOC101168718

0.948

LOC101161353

0.948

LOC101167719

0.915

LOC101168962

0.821

LOC101157684

0.786

dact2

0.563

comt

0.558

bdnf

0.558

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101157684	LOC101161353	ENSORLP00000033208	ENSORLP00000017728	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	0.747
LOC101157684	LOC101165845	ENSORLP00000033208	ENSORLP00000041570	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1.	0.792
LOC101157684	LOC101167719	ENSORLP00000033208	ENSORLP00000005961	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	Uncharacterized protein.	0.553
LOC101157684	LOC101168718	ENSORLP00000033208	ENSORLP00000007128	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	Uncharacterized protein.	0.747
LOC101157684	LOC101168962	ENSORLP00000033208	ENSORLP00000007142	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	Guanine nucleotide binding protein (G protein), alpha 14a.	0.747
LOC101157684	htr2a	ENSORLP00000033208	ENSORLP00000017544	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a.	0.786
LOC101157684	htr2b	ENSORLP00000033208	ENSORLP00000009451	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled.	0.812
LOC101161353	LOC101157684	ENSORLP00000017728	ENSORLP00000033208	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	0.747
LOC101161353	LOC101165845	ENSORLP00000017728	ENSORLP00000041570	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1.	0.950
LOC101161353	LOC101167719	ENSORLP00000017728	ENSORLP00000005961	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	Uncharacterized protein.	0.901
LOC101161353	LOC101168718	ENSORLP00000017728	ENSORLP00000007128	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	Uncharacterized protein.	0.910
LOC101161353	LOC101168962	ENSORLP00000017728	ENSORLP00000007142	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	Guanine nucleotide binding protein (G protein), alpha 14a.	0.545
LOC101161353	htr2a	ENSORLP00000017728	ENSORLP00000017544	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a.	0.948
LOC101161353	htr2b	ENSORLP00000017728	ENSORLP00000009451	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled.	0.955
LOC101165845	LOC101157684	ENSORLP00000041570	ENSORLP00000033208	5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1.	Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.	0.792
LOC101165845	LOC101161353	ENSORLP00000041570	ENSORLP00000017728	5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1.	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	0.950
LOC101165845	LOC101167719	ENSORLP00000041570	ENSORLP00000005961	5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1.	Uncharacterized protein.	0.915
LOC101165845	LOC101168718	ENSORLP00000041570	ENSORLP00000007128	5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1.	Uncharacterized protein.	0.950
LOC101165845	LOC101168962	ENSORLP00000041570	ENSORLP00000007142	5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1.	Guanine nucleotide binding protein (G protein), alpha 14a.	0.826
LOC101165845	htr2a	ENSORLP00000041570	ENSORLP00000017544	5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1.	5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a.	0.980