STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sh3kbp1SH3-domain kinase binding protein 1. (590 aa)    
Predicted Functional Partners:
ubc
Ubiquitin B.
    
  0.804
rps27a
Ribosomal protein S27a.
    
  0.802
capzb
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
    
 
 0.756
cbl
Cbl proto-oncogene, E3 ubiquitin protein ligase.
    
 0.730
LOC101163758
Uncharacterized protein.
    
 0.730
LOC101158476
Cbl proto-oncogene C, E3 ubiquitin protein ligase.
    
 0.730
cblb
Cbl proto-oncogene B, E3 ubiquitin protein ligase.
    
 0.727
nphs1
NPHS1 adhesion molecule, nephrin.
    
 0.719
LOC101162065
B cell linker.
    
 0.713
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.700
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.