STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
comtCatechol-O-methyltransferase b. (264 aa)    
Predicted Functional Partners:
LOC101175668
Amine oxidase.
     
 0.968
maob
Amine oxidase.
     
 0.964
LOC101159216
Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.
   
 
 0.933
cyp1a
Cytochrome P450 1A1; Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
   
 
 0.929
ddc
Uncharacterized protein.
   
 
 0.929
dbh
Dopamine beta-hydroxylase (dopamine beta-monooxygenase).
     
 0.928
pnmt
Uncharacterized protein.
     
 0.924
LOC101157544
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.921
aldh3b1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.921
LOC101165493
Transmembrane O-methyltransferase.
  
  
 
0.905
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.