STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2MHV7_ORYLAVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (649 aa)    
Predicted Functional Partners:
Unc79
Uncharacterized protein.
   
 0.991
ENSORLP00000040805
EF-hand domain-containing protein.
 
   
  0.989
ENSORLP00000045265
Uncharacterized protein.
 
  
  0.963
Cacna1d
Calcium channel, voltage-dependent, L type, alpha 1D subunit, b.
 
   
  0.908
LOC101173517
Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
  
  
 
0.901
H2LT96_ORYLA
EF-hand domain-containing protein.
 
   
  0.869
LOC101156213
Calcium channel, voltage-dependent, alpha 2/delta subunit 1a.
   
 0.780
cacna2d1
Calcium voltage-gated channel auxiliary subunit alpha2delta 1.
   
 0.780
LOC101156079
Calcium channel, voltage-dependent, alpha 2/delta subunit 2b.
   
 0.780
cacna2d2
Calcium channel, voltage-dependent, alpha 2/delta subunit 2a.
   
 0.780
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.