STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tirapToll-interleukin 1 receptor (TIR) domain containing adaptor protein. (252 aa)    
Predicted Functional Partners:
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
    
0.992
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.990
irak4
Interleukin-1 receptor-associated kinase 4.
   
 0.979
LOC101166698
Protein kinase domain-containing protein.
   
 0.965
LOC101155381
Toll-like receptor 18.
   
 0.957
LOC101163128
TIR domain-containing protein; Belongs to the Toll-like receptor family.
   
 0.941
Tep1
Uncharacterized protein.
   
   0.824
yipf4
Protein YIPF.
      
 0.794
LOC101174929
Toll-like receptor 1; Belongs to the Toll-like receptor family.
  
 0.704
LOC101162959
TIR domain-containing protein.
   
 0.656
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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