STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccne2Cyclin E2; Belongs to the cyclin family. (393 aa)    
Predicted Functional Partners:
rbl1
Retinoblastoma-like 1 (p107).
   
 0.989
cdk2
Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily.
   
 0.989
rb1
Retinoblastoma 1.
   
 0.988
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
    
 0.985
LOC101166216
Cyclin-dependent kinase inhibitor 1A.
   
 0.981
LOC101160207
Uncharacterized protein.
   
 0.981
cdkn1b
Cyclin-dependent kinase inhibitor 1Bb.
   
 0.981
cdkn1c
Uncharacterized protein.
   
 0.981
skp2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.
   
 0.980
cul1
Cullin 1b; Belongs to the cullin family.
    
 0.979
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.