STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
edarTumor necrosis factor receptor superfamily member EDAR; Receptor for EDA (By similarity). May mediate the activation of NF-kappa-B and JNK. (514 aa)    
Predicted Functional Partners:
eda
Ectodysplasin A; Belongs to the tumor necrosis factor family.
    
 0.997
edaradd
EDAR-associated death domain.
    
 0.919
lef1
Lymphoid enhancer-binding factor 1.
      
 0.701
LOC100049240
Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family.
      
 0.690
furin
Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family.
      
 0.690
tcf7
Transcription factor 7.
      
 0.659
nanos2
Nanos-type domain-containing protein; Belongs to the nanos family.
    
 0.635
nanos3
NANOS3; Belongs to the nanos family.
    
 0.635
nanos1a
NANOS1A; Belongs to the nanos family.
    
 0.635
shh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
      
 0.614
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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