STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101173974Presenilin associated, rhomboid-like a. (383 aa)    
Predicted Functional Partners:
stoml2
Stomatin (EPB72)-like 2.
   
 0.704
LOC101170791
YME1-like 1b.
   
 
 0.674
yme1l1
YME1-like 1a.
   
 
 0.674
phb2
Prohibitin.
   
 0.643
pink1
PTEN induced kinase 1.
    
 
 0.621
spg7
SPG7 matrix AAA peptidase subunit, paraplegin.
   
 
 0.511
prkn
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 
 0.500
opa1
OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
   
 
 0.490
pgam5
PGAM family member 5, serine/threonine protein phosphatase, mitochondrial.
   
  
 0.479
mthfsd
Methenyltetrahydrofolate synthetase domain containing.
  
    0.470
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (14%) [HD]