STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arafA-Raf proto-oncogene, serine/threonine kinase. (607 aa)    
Predicted Functional Partners:
map2k2
Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.
   
0.981
map2k1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
   
0.981
hras
HRas proto-oncogene, GTPase a.
   
 0.976
LOC101154954
Zgc:55558.
   
 0.976
kras
GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation.
   
 0.976
mras
Muscle RAS oncogene homolog.
   
 0.965
LOC101174431
RAS related.
   
 0.962
rras2
RAS related 2.
   
 0.962
braf
B-Raf proto-oncogene, serine/threonine kinase.
  
  
 
0.907
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
  
  
 
0.906
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.