STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
foxa2Hepatocyte nuclear factor 3-beta; Transcription activator for a number of liver genes. Interacts with the cis-acting regulatory regions of these genes (By similarity). (415 aa)    
Predicted Functional Partners:
sox17
SRY-box containing gene 17.
    
 
 0.730
gata4
GATA binding protein 4.
    
 0.687
gata6
GATA binding protein 6.
    
 0.670
gata5
GATA binding protein 5.
    
 0.653
shh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
     
 0.647
nrip1
Nuclear receptor interacting protein 1b.
     
 0.627
pgr
Uncharacterized protein.
    
 0.621
gata2
Transcription factor GATA-2.
    
 0.615
LOC101161391
GATA binding protein 2a.
    
 0.615
gata3
Uncharacterized protein.
    
 0.615
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.