STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmem86aTransmembrane protein 86A. (237 aa)    
Predicted Functional Partners:
dlst
Dihydrolipoamide S-succinyltransferase.
      
 0.666
ppp1r14b
Protein phosphatase 1, regulatory (inhibitor) subunit 14Bb.
      
 0.661
map2k5
Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily.
      
 0.660
vac14
Vac14 homolog (S. cerevisiae).
      
 0.618
ZDHHC18
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
      
 0.615
JAZF1
JAZF zinc finger 1b.
      
 0.577
get3
ATPase get3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]
      
 0.559
c14h11orf54
Zgc:85789.
      
 0.559
slc30a5
Solute carrier family 30 member 5.
   
  
 0.537
ktn1
Kinectin 1.
      
 0.529
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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