STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpx2TPX2 microtubule nucleation factor. (705 aa)    
Predicted Functional Partners:
aurkb
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.949
aurka
Aurora kinase A; Belongs to the protein kinase superfamily.
   
 0.949
dlgap5
Discs, large (Drosophila) homolog-associated protein 5.
   
  
 0.927
LOC101155061
Baculoviral IAP repeat containing 5a.
   
 0.915
ube2c
Ubiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family.
   
  
 0.909
kif11
Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.901
nusap1
Nucleolar and spindle associated protein 1.
   
 
 0.899
LOC101165832
Kinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.891
bub1
BUB1 mitotic checkpoint serine/threonine kinase.
   
  
 0.890
melk
Non-specific serine/threonine protein kinase.
   
 
 0.889
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.