STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cdk1Cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. Component of the kinase complex that phosphorylates the repetitive C- terminus of RNA polymerase II. Catalytic component of MPF (By similarity); Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. (303 aa)    
Predicted Functional Partners:
ccnb1
G2/mitotic-specific cyclin-B1; Essential for the control of the cell cycle at the G2/M (mitosis) transition; Belongs to the cyclin family. Cyclin AB subfamily.
   
 0.998
ccna1
Cyclin A1; Belongs to the cyclin family.
   
 0.991
cdc25b
Rhodanese domain-containing protein.
   
 0.990
ccna2
Cyclin A2; Belongs to the cyclin family.
   
 0.989
LOC101162061
Cyclin N-terminal domain containing 2; Belongs to the cyclin family.
   
 0.985
ccnb3
Cyclin B3; Belongs to the cyclin family.
   
 0.983
ccnh
Cyclin H; Belongs to the cyclin family.
    
 0.981
LOC101156733
Wee1-like protein kinase.
   
0.978
PLK1
Serine/threonine-protein kinase PLK.
   
0.978
wee1
Wee1-like protein kinase.
   
0.977
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.