STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icmtProtein-S-isoprenylcysteine O-methyltransferase. (291 aa)    
Predicted Functional Partners:
zmpste24
CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.
    
 0.967
rce1
Ras converting CAAX endopeptidase 1a.
   
 0.960
fnta
Farnesyltransferase, CAAX box, alpha.
      
 0.674
ENSORLP00000043660
Uncharacterized protein.
   
 0.622
rcc1
Regulator of chromosome condensation 1.
   
  
 0.581
LOC101156149
Uncharacterized protein.
    
 0.580
hras
HRas proto-oncogene, GTPase a.
    
 0.580
LOC101154954
Zgc:55558.
    
 0.580
LOC101157118
V-ral simian leukemia viral oncogene homolog Ba (ras related).
    
 0.580
kras
GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation.
    
 0.580
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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