STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
H2MZ79_ORYLASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (463 aa)    
Predicted Functional Partners:
Unc79
Uncharacterized protein.
   
 0.991
ENSORLP00000030101
Ion_trans domain-containing protein.
 
     0.929
ENSORLP00000030494
Ion_trans domain-containing protein.
 
    
0.922
wdr35
WD repeat-containing protein 35.
    
 0.654
ENSORLP00000044666
Ion_trans domain-containing protein.
 
0.641
ENSORLP00000042482
Ion_trans domain-containing protein.
 
0.640
IFT122
Intraflagellar transport 122.
   
 0.639
wdr19
WD repeat domain 19.
    
 0.617
ift140
Intraflagellar transport 140 homolog (Chlamydomonas).
    
 0.617
scn2b
Sodium channel, voltage-gated, type II, beta.
   
 0.613
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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