STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdgfraPlatelet-derived growth factor receptor, alpha polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1460 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
   
 0.976
pdgfa
Platelet-derived growth factor alpha polypeptide b; Belongs to the PDGF/VEGF growth factor family.
    
 0.969
LOC101171139
Platelet-derived growth factor alpha polypeptide a; Belongs to the PDGF/VEGF growth factor family.
    
 0.945
pdgfb
Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family.
   
 0.938
SRC
Tyrosine-protein kinase.
   
0.936
LOC101164480
Tyrosine-protein kinase.
   
0.936
sos2
Son of sevenless homolog 2 (Drosophila).
    
 0.928
vegfc
PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.
    
 0.891
Kitlg
Kit ligand a.
    
 0.874
fgf4
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
   
 0.859
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.