STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101175466Uncharacterized protein. (494 aa)    
Predicted Functional Partners:
sav1
Salvador family WW domain containing protein 1.
    
 0.965
LOC100049265
Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.
   
  0.943
casp3
Uncharacterized protein; Belongs to the peptidase C14A family.
   
  0.943
LOC111948337
LIM zinc-binding domain-containing protein.
    
 0.925
foxo3
Forkhead box O5.
    
 0.919
foxo1
Fork-head domain-containing protein.
    
 0.919
LOC110015734
Forkhead box O4.
    
 0.919
LOC101164740
Fork-head domain-containing protein.
    
 0.917
yap1
Transcriptional coactivator YAP1; Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (By similarity). Plays a key role in tissue tension and 3D tissue shape by regulating cortical actomyosin network formation.
    
 0.915
LOC101175251
MOB kinase activator 1Bb.
   
 0.905
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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