STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101171466Galectin. (296 aa)    
Predicted Functional Partners:
LOC101164514
SKICH domain-containing protein.
    
 
 0.824
ttc13
Tetratricopeptide repeat domain 13.
   
 
 0.515
ubr7
UBR-type domain-containing protein.
      
 0.505
LOC101174971
Ubiquitin protein ligase E3 component n-recognin 7.
      
 0.505
TRIM67
Tripartite motif containing 67.
      
 0.505
rnf19b
RBR-type E3 ubiquitin transferase.
      
 0.505
rnf217
RBR-type E3 ubiquitin transferase.
      
 0.501
rnf8
E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]
      
 0.489
tax1bp1
Tax1 (human T-cell leukemia virus type I) binding protein 1b.
   
 
 0.477
LOC101155046
Proteasome subunit alpha type.
   
  
 0.441
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.