igf1 protein (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

igf1

Insulin-like growth factor 1. (199 aa)

Predicted Functional Partners:

LOC101173298

0.938

LOC101163560

0.933

LOC101166254

0.919

IGFBP3

0.913

LOC101162674

0.913

LOC100125446

0.912

LOC101172253

0.912

LOC101174210

0.684

met

0.656

LOC101158510

0.656

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IGFBP3	LOC101162674	ENSORLP00000021459	ENSORLP00000045746	Insulin like growth factor binding protein 3.	Insulin-like growth factor binding protein 3.	0.902
IGFBP3	LOC101163560	ENSORLP00000021459	ENSORLP00000029312	Insulin like growth factor binding protein 3.	Tyrosine-protein kinase receptor.	0.487
IGFBP3	LOC101173298	ENSORLP00000021459	ENSORLP00000030267	Insulin like growth factor binding protein 3.	Tyrosine-protein kinase receptor.	0.411
IGFBP3	igf1	ENSORLP00000021459	ENSORLP00000026564	Insulin like growth factor binding protein 3.	Insulin-like growth factor 1.	0.913
LOC100125446	LOC101158510	ENSORLP00000034276	ENSORLP00000025001	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Eph receptor A2 b.	0.722
LOC100125446	LOC101163560	ENSORLP00000034276	ENSORLP00000029312	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.979
LOC100125446	LOC101166254	ENSORLP00000034276	ENSORLP00000043238	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.979
LOC100125446	LOC101172253	ENSORLP00000034276	ENSORLP00000044694	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.902
LOC100125446	LOC101173298	ENSORLP00000034276	ENSORLP00000030267	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.979
LOC100125446	LOC101174210	ENSORLP00000034276	ENSORLP00000041353	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Protein kinase domain-containing protein.	0.731
LOC100125446	igf1	ENSORLP00000034276	ENSORLP00000026564	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin-like growth factor 1.	0.912
LOC100125446	met	ENSORLP00000034276	ENSORLP00000024532	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	MET proto-oncogene, receptor tyrosine kinase.	0.746
LOC101158510	LOC100125446	ENSORLP00000025001	ENSORLP00000034276	Eph receptor A2 b.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.722
LOC101158510	LOC101172253	ENSORLP00000025001	ENSORLP00000044694	Eph receptor A2 b.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.722
LOC101158510	igf1	ENSORLP00000025001	ENSORLP00000026564	Eph receptor A2 b.	Insulin-like growth factor 1.	0.656
LOC101162674	IGFBP3	ENSORLP00000045746	ENSORLP00000021459	Insulin-like growth factor binding protein 3.	Insulin like growth factor binding protein 3.	0.902
LOC101162674	igf1	ENSORLP00000045746	ENSORLP00000026564	Insulin-like growth factor binding protein 3.	Insulin-like growth factor 1.	0.913
LOC101163560	IGFBP3	ENSORLP00000029312	ENSORLP00000021459	Tyrosine-protein kinase receptor.	Insulin like growth factor binding protein 3.	0.487
LOC101163560	LOC100125446	ENSORLP00000029312	ENSORLP00000034276	Tyrosine-protein kinase receptor.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.979
LOC101163560	LOC101166254	ENSORLP00000029312	ENSORLP00000043238	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.902