Herc1 protein (Oryzias latipes) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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Textmining

[Homology]

Score

Herc1

Uncharacterized protein. (523 aa)

Predicted Functional Partners:

ENSORLP00000032585

0.942

ENSORLP00000027360

0.936

ENSORLP00000038063

0.923

ENSORLP00000043917

0.923

ENSORLP00000034842

0.920

ENSORLP00000034897

0.916

ENSORLP00000032403

0.905

ENSORLP00000038161

0.878

rnf8

0.625

LOC101160447

0.525

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSORLP00000027360	ENSORLP00000032403	ENSORLP00000027360	ENSORLP00000032403	Uncharacterized protein.	Uncharacterized protein.	0.900
ENSORLP00000027360	ENSORLP00000034842	ENSORLP00000027360	ENSORLP00000034842	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.931
ENSORLP00000027360	ENSORLP00000034897	ENSORLP00000027360	ENSORLP00000034897	Uncharacterized protein.	HECT domain-containing protein.	0.937
ENSORLP00000027360	ENSORLP00000038063	ENSORLP00000027360	ENSORLP00000038063	Uncharacterized protein.	HECT domain-containing protein.	0.941
ENSORLP00000027360	ENSORLP00000038161	ENSORLP00000027360	ENSORLP00000038161	Uncharacterized protein.	Uncharacterized protein.	0.899
ENSORLP00000027360	ENSORLP00000043917	ENSORLP00000027360	ENSORLP00000043917	Uncharacterized protein.	Uncharacterized protein.	0.927
ENSORLP00000027360	Herc1	ENSORLP00000027360	ENSORLP00000026955	Uncharacterized protein.	Uncharacterized protein.	0.936
ENSORLP00000027360	LOC101160447	ENSORLP00000027360	ENSORLP00000038127	Uncharacterized protein.	RAN binding protein 2.	0.525
ENSORLP00000027360	rnf8	ENSORLP00000027360	ENSORLP00000015004	Uncharacterized protein.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.625
ENSORLP00000032403	ENSORLP00000027360	ENSORLP00000032403	ENSORLP00000027360	Uncharacterized protein.	Uncharacterized protein.	0.900
ENSORLP00000032403	ENSORLP00000032585	ENSORLP00000032403	ENSORLP00000032585	Uncharacterized protein.	Uncharacterized protein.	0.900
ENSORLP00000032403	ENSORLP00000034842	ENSORLP00000032403	ENSORLP00000034842	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.900
ENSORLP00000032403	ENSORLP00000034897	ENSORLP00000032403	ENSORLP00000034897	Uncharacterized protein.	HECT domain-containing protein.	0.899
ENSORLP00000032403	ENSORLP00000038063	ENSORLP00000032403	ENSORLP00000038063	Uncharacterized protein.	HECT domain-containing protein.	0.899
ENSORLP00000032403	ENSORLP00000043917	ENSORLP00000032403	ENSORLP00000043917	Uncharacterized protein.	Uncharacterized protein.	0.900
ENSORLP00000032403	Herc1	ENSORLP00000032403	ENSORLP00000026955	Uncharacterized protein.	Uncharacterized protein.	0.905
ENSORLP00000032403	LOC101160447	ENSORLP00000032403	ENSORLP00000038127	Uncharacterized protein.	RAN binding protein 2.	0.521
ENSORLP00000032585	ENSORLP00000032403	ENSORLP00000032585	ENSORLP00000032403	Uncharacterized protein.	Uncharacterized protein.	0.900
ENSORLP00000032585	ENSORLP00000034842	ENSORLP00000032585	ENSORLP00000034842	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.944
ENSORLP00000032585	ENSORLP00000034897	ENSORLP00000032585	ENSORLP00000034897	Uncharacterized protein.	HECT domain-containing protein.	0.935