STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
slf1SMC5-SMC6 complex localization factor 1. (900 aa)    
Predicted Functional Partners:
atr
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
    
 0.996
cdc45
CDC45 cell division cycle 45 homolog (S. cerevisiae).
   
 
 0.995
bard1
BRCA1 associated RING domain 1.
   
0.995
rad17
RAD17 checkpoint clamp loader component.
  
 0.985
rad1
RAD1 homolog (S. pombe).
    
 0.984
dna2
DNA replication helicase/nuclease 2.
   
 0.982
exo1
Exonuclease 1.
   
 0.980
rfc4
Replication factor C (activator 1) 4.
  
 0.979
rad50
RAD50 homolog, double strand break repair protein.
   
 0.979
mre11
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
   
 0.978
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.