STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
npc2Niemann-Pick disease, type C2. (149 aa)    
Predicted Functional Partners:
npc1
Niemann-Pick disease, type C1.
   
 0.997
NPC1L1
NPC1 like intracellular cholesterol transporter 1.
   
 0.962
scap
SREBF chaperone.
   
 0.883
H2MBB3_ORYLA
Vitellogenin domain-containing protein.
     
 0.596
LOC101158990
Apolipoprotein Bb, tandem duplicate 2.
     
 0.596
LOC101156458
Apolipoprotein Ba.
     
 0.596
stard3
StAR-related lipid transfer (START) domain containing 3.
      
 0.560
chmp7
Charged multivesicular body protein 7.
      
 0.559
acp5
Tartrate-resistant acid phosphatase type 5.
   
  
 0.528
vit-6
Uncharacterized protein.
     
 0.527
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.