STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
edem2alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (567 aa)    
Predicted Functional Partners:
trpc4ap
Transient receptor potential cation channel, subfamily C, member 4 associated protein a.
 
 
  
 0.911
phf20
PHD finger protein 20, a.
      
 0.833
txndc11
Thioredoxin domain containing 11.
   
 
 0.793
derl2
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
   
 
 0.767
sel1l
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
   
 
 0.766
os9
OS9 endoplasmic reticulum lectin.
    
 
 0.722
xbp1
X-box binding protein 1.
     
 0.707
canx
Calnexin.
   
 
 0.701
ndrg3
Ndrg family member 3a.
      
 0.623
NDRG3
NDRG family member 3.
      
 0.623
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.