STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101173298Tyrosine-protein kinase receptor. (1408 aa)    
Predicted Functional Partners:
LOC101174984
Insulin receptor substrate 2a.
   
 0.980
LOC100125446
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.979
LOC101172253
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.979
irs2
Insulin receptor substrate 2b.
   
 0.972
LOC101165750
Si:ch211-284e13.4.
   
 0.971
LOC101163034
Si:ch73-335l21.1.
   
 0.971
LOC101169068
Insulin receptor substrate 4a.
   
 0.971
grb10
Growth factor receptor-bound protein 10b.
    
 0.959
grb2
Growth factor receptor-bound protein 2b.
   
 0.955
igf1
Insulin-like growth factor 1.
   
 
 0.938
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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