STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
piwil1Uncharacterized protein; Belongs to the argonaute family. (1185 aa)    
Predicted Functional Partners:
tdrd1
Tudor domain-containing protein 1; Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of corr [...]
   
 0.932
amh-2
Uncharacterized protein.
   
 0.901
tdrd5
Uncharacterized protein.
   
 0.887
H2MMA0_ORYLA
Tudor domain containing 9.
   
 0.862
tdrkh
Tudor and KH domain containing.
   
 0.859
LOC101169997
Si:dkeyp-93d12.1.
   
 0.838
rnf17
Ring finger protein 17.
   
 0.834
nanos3
NANOS3; Belongs to the nanos family.
   
 
 0.795
dazl
RRM domain-containing protein.
   
 
 0.786
tdrd7
Tudor domain containing 7 b.
   
 0.784
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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