STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bub1BUB1 mitotic checkpoint serine/threonine kinase. (1115 aa)    
Predicted Functional Partners:
mad2l1
HORMA domain-containing protein.
   
 0.998
bub3
BUB3 mitotic checkpoint protein.
   
 0.997
ndc80
NDC80 kinetochore complex component.
   
 0.994
mad1l1
Mitotic arrest deficient 1 like 1.
    
 0.994
nuf2
UF2 component of NDC80 kinetochore complex.
   
 0.989
LOC101160375
Uncharacterized protein.
   
0.987
bub1b
BUB1 N-terminal domain-containing protein.
   
0.987
cdc20
WD_REPEATS_REGION domain-containing protein.
   
 0.985
cdc20b
WD_REPEATS_REGION domain-containing protein.
   
 0.981
nek2
NIMA-related kinase 2.
   
 0.978
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.