STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lep-bLeptin-B; May function as part of a signaling pathway that acts to regulate the size of the body fat depot. (158 aa)    
Predicted Functional Partners:
lepr
Leptin recepter.
     
 0.964
lepa
Leptin-A; May function as part of a signaling pathway that acts to regulate the size of the body fat depot.
      
 0.813
lrrc4
Leucine rich repeat containing 4.2.
      
 0.506
leprotl1
Leptin receptor overlapping transcript like 1.
      
 0.501
LOC101163155
Nucleobindin 2a.
      
 0.484
LOC101169036
Nucleobindin 1.
      
 0.467
NUCB2
Nucleobindin 2.
      
 0.461
sp9
Sp9 transcription factor.
      
 0.441
LOC101157210
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
      
 0.437
LOC101168830
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
      
 0.437
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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