STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101157822NK2 homeobox 2a. (279 aa)    
Predicted Functional Partners:
olig2
Oligodendrocyte lineage transcription factor 2.
   
 0.706
ENSORLP00000032832
BHLH domain-containing protein.
   
 0.570
ptch2
Patched 2.
      
 0.549
prdm8
PR domain containing 8b.
      
 0.545
neurod1
Neurogenic differentiation factor.
   
 0.494
neurog1
Neurogenin 1.
   
 0.461
ENSORLP00000041481
Oligodendrocyte transcription factor 1.
   
 0.447
hhip
Hedgehog interacting protein.
      
 0.440
nkx6-1
NK6 homeobox 1.
   
  
0.425
LOC100125446
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.421
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.