STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zer1Zyg-11 related, cell cycle regulator. (785 aa)    
Predicted Functional Partners:
cul2
Cullin 2; Belongs to the cullin family.
    
 0.923
fpgs
Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family.
      
 0.816
zyg11b
Zyg-11 homolog (C. elegans).
     
0.686
eloc
Elongin C paralog b; Belongs to the SKP1 family.
    
 
 0.670
appbp2
Amyloid beta precursor protein (cytoplasmic tail) binding protein 2.
     
 0.578
vhl
Von Hippel-Lindau tumor suppressor.
   
  
 0.563
lrr1
Zgc:77287.
      
 0.560
snx11
PX domain-containing protein.
      
 0.558
zswim8
Zinc finger, SWIM-type containing 8.
     
 0.553
LOC101165407
Zinc finger, SWIM-type containing 6.
     
 0.541
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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