STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101171576Multiple EGF-like-domains 11. (1085 aa)    
Predicted Functional Partners:
LOC101164872
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
      
 0.651
ppp2ca
Serine/threonine-protein phosphatase.
      
 0.603
CSK
Tyrosine-protein kinase.
    
 0.586
adcy7
Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
      
 0.569
gulp1
GULP PTB domain containing engulfment adaptor 1a.
   
 
 0.551
ccne1
Cyclin E1; Belongs to the cyclin family.
      
 0.538
RAB11A
RAB11A, member RAS oncogene family.
     
 0.524
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
      
 0.515
gas1
Growth arrest-specific 1a.
      
 0.510
itga3
Integrin, alpha 3b; Belongs to the integrin alpha chain family.
    
 0.507
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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